BDBM47167 CHEMBL201511::US8957103, Z1::US9364459, A

SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12

InChI Key InChIKey=CZGMEOAMQWAJOY-UHFFFAOYSA-N

Data  61 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 47167   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  90nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  90nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  26nMAssay Description:Inhibition of VEGFR2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg—Universitat Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of VEGFR2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed